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NDT Advance Access originally published online on August 6, 2008
Nephrology Dialysis Transplantation 2008 23(10):3063-3064; doi:10.1093/ndt/gfn458
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


New insights into intestinal iron absorption*

Walter H. Hörl

Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Vienna, Austria

Walter H. Hörl, Division of Nephrology and Dialysis, Department of Medicine III, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Vienna, Austria. Tel: +43-1-40-400-4390; Fax: +43-1-40-400-4392; E-mail: walter.hoerl@meduniwien.ac.at

Keywords: intestinal iron absorption

The first 10% of the full text of this article appears below.



   Introduction
 
In the May issue of Science, Du et al. described the novel and exciting finding that the transmembrane serine protease 6 (TMPRSS6) senses iron deficiency [1]. In their study, Du et al. described a mutant mouse, which is characterized by progressive loss of body hair and microcytic anaemia. The phenotype was found to result from reduced intestinal iron absorption caused by high levels of hepcidin. Iron deprivation and . . . [Full Text of this Article]



   (Patho-)Physiology of enteric iron uptake
 


   What is in it for the practising nephrologist?
 


   Take home message
 

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