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Nephrology Dialysis Transplantation 2008 23(6):1805-1808; doi:10.1093/ndt/gfn292
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© The Author [2008]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org


Sunscreens in organ transplant patients

Claas Ulrich1, A. Degen2, Manisha J. Patel3 and Eggert Stockfleth1

1 Department of Dermatology, Skin Cancer Center Charité, Universitätsmedizin Charité, Berlin 2 Department of Dermatology and Allergology, Hannover Medical University, Germany 3 Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Correspondence and offprint requests to: Claas Ulrich, Department of Dermatology, Skin Cancer Center Charité, Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany. Tel: +49-3-0450-518005; Fax: +49-3-0450-518905; E-mail: Claas.Ulrich@charite.de

Keywords: organ transplant patients; skin cancer prevention; sunscreen; UV light

The first 150 words of the full text of this article appear below.



   Introduction
 
Non-melanoma skin cancer, specifically basal cell carcinoma and squamous cell carcinoma, is the most frequent type of cancers diagnosed in fair-skinned populations. Their respective incidence is increasing worldwide by 3–5% per year [1].

Ultraviolet radiation is a major environmental cause. Both the total cumulative lifetime exposure to UV radiation and sporadic patterns of sun exposure (i.e. chronic, during work versus intermittent, during leisure time) are determinants for the individual risk of skin cancer. Increased cumulative lifetime sun exposure is associated with an increased risk of squamous cell carcinoma and actinic keratosis, the latter representing possible precursors of invasive squamous cell carcinoma [2].



   Epidemiology in organ transplant recipients
 
Organ transplant recipients have particularly high rates of squamous cell carcinoma with a relative risk ~100-fold higher than that in the immunocompetent population [3].

In an Irish study of renal transplant recipients, 93.5% of all squamous cell carcinomas occurred on the traditional . . . [Full Text of this Article]



   The role of immune suppression
 


   Is UV radiation-induced skin damage avoidable?
 


   Sunscreens—could they be the solution?
 


   Is there evidence of benefit?
 


   Conclusion
 

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